Multisystem Toxicity in Cancer: Lessons from NASA’s Countermeasures Program

Astronauts and cancer patients are subject to similar multisystem physiological toxicities. Over the past sixty years, NASA developed a state-of-the-art countermeasures program (CMP) to characterize and mitigate the physiological consequences of spaceflight. Here, we propose a NASA-modeled CMP to el...

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Bibliographic Details
Published inCell Vol. 179; no. 5; pp. 1003 - 1009
Main Authors Scott, Jessica M., Dolan, Lianne B., Norton, Larry, Charles, John B., Jones, Lee W.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 14.11.2019
Subjects
Astronauts
Humans
Medical Countermeasures
neoplasms
Neoplasms - pathology
patients
Space Flight
toxicity
United States
United States National Aeronautics and Space Administration
United States
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Summary:Astronauts and cancer patients are subject to similar multisystem physiological toxicities. Over the past sixty years, NASA developed a state-of-the-art countermeasures program (CMP) to characterize and mitigate the physiological consequences of spaceflight. Here, we propose a NASA-modeled CMP to elucidate and abrogate physiological toxicities in patients with cancer. Astronauts and cancer patients are subject to similar multisystem physiological toxicities. Over the past sixty years, NASA developed a state-of-the-art countermeasures program (CMP) to characterize and mitigate the physiological consequences of spaceflight. Here, we propose a NASA-modeled CMP to elucidate and abrogate physiological toxicities in patients with cancer.
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ISSN:0092-8674
1097-4172
1097-4172
DOI:10.1016/j.cell.2019.10.024