Granulomatous hepatitis caused by Q fever: a differential diagnosis of fever of unknown origin

The differential diagnosis of fever of unknown origin (FUO) includes infectious, neoplastic, rheumaticinflammatory and miscellaneous diseases. We report the case of a 35-year-old man with FUO caused by Q fever. A liver biopsy showed the characteristic fibrin-ring lipogranulomas compatible with Q fev...

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Published inAnnals of hepatology Vol. 12; no. 1; pp. 138 - 141
Main Authors Aguilar-Olivos, Nancy, del Carmen Manzano-Robleda, María, Gutiérrez-Grobe, Ylse, Chablé-Montero, Fredy, Albores-Saavedra, Jorge, López-Méndez, Eric
Format Journal Article
LanguageEnglish
Published Mexico Elsevier 01.01.2013
Subjects
Adult
Biopsy
Coxiella burnetii
Diagnosis, Differential
Fever of Unknown Origin - etiology
Granuloma - pathology
Granulomatous diseases
Hepatitis, Viral, Human - pathology
Histopathology
Humans
Liver
Liver - pathology
Male
Q Fever - complications
Q Fever - pathology
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Summary:The differential diagnosis of fever of unknown origin (FUO) includes infectious, neoplastic, rheumaticinflammatory and miscellaneous diseases. We report the case of a 35-year-old man with FUO caused by Q fever. A liver biopsy showed the characteristic fibrin-ring lipogranulomas compatible with Q fever. The serologic tests confirmed the diagnosis of acute infection by Coxiella burnetii. The therapeutic response was excellent. In conclusion, we described a patient with acute Q fever and granulomatous hepatitis.
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ISSN:1665-2681
DOI:10.1016/s1665-2681(19)31396-1