Polyelectrolyte Complex Membranes for Immobilizing Biomolecules, and Their Applications to Bio-analysis

The immobilization of biomolecules is an important technique for bio-analysis, and can be applied to biosensors with both high selectivity and high sensitivity. Many researchers have developed immobilization techniques to optimize these characteristics. In the last two decades, an immobilization tec...

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Bibliographic Details
Published inAnalytical Sciences Vol. 27; no. 7; p. 695
Main Author YABUKI, Soichi
Format Journal Article
LanguageEnglish
Published Singapore The Japan Society for Analytical Chemistry 2011
Springer Nature Singapore
Japan Science and Technology Agency
Subjects
Adsorption
Analytical Chemistry
Biosensing Techniques - methods
Biosensors
Chemistry
Chemistry Techniques, Analytical - methods
Electrolytes - chemistry
Membranes, Artificial
Polyelectrolytes
Polymers - chemistry
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Summary:The immobilization of biomolecules is an important technique for bio-analysis, and can be applied to biosensors with both high selectivity and high sensitivity. Many researchers have developed immobilization techniques to optimize these characteristics. In the last two decades, an immobilization technique that meets the desired requirements was developed by using polyelectrolytes to form complexes, based on the electrostatic binding between polycations and polyanions. This review summarizes the techniques used for the immobilization of biomolecules by polyelectrolyte complexes; it also discusses related subjects.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
ISSN:0910-6340
1348-2246
DOI:10.2116/analsci.27.695