RFID Tag Helix Antenna Sensors for Wireless Drug Dosage Monitoring

• Published in: IEEE journal of translational engineering in health and medicine Vol. 2; pp. 1 - 8
• Main Authors: Haiyu Huang, Peisen Zhao, Pai-Yen Chen, Yong Ren, Xuewu Liu, Ferrari, Mauro, Ye Hu, Akinwande, Deji
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.01.2014
• Subjects: Drug delivery; Drug delivery system; electrically small antenna; Helical antennas; helix antenna; medical implants; Radiofrequency identification; Resonant frequency; RFID; RFID tags; Sensors; Tagging; Wireless communication; wireless sensor; electrically small antenna; helix antenna; RFID; medical implants; wireless sensor; Drug delivery system
• ISSN: 2168-2372; 2168-2372
• DOI: 10.1109/JTEHM.2014.2309335

Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μ l/MHz for transdermal drug delivery monitoring and 2.76- μ l/MHz sensitivity for implanted drug delivery monitoring.