Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection

Cryptococcus neoformans is a saprophytic fungus that causes fatal disseminated infections in immunocompromised hosts. Since the onset of the COVID-19 pandemic, multiple cases of secondary viral, bacterial, and fungal infections have been reported in patients after SARS-CoV-2 infection. We describe h...

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Published inCase reports in infectious diseases Vol. 2021; pp. 1 - 3
Main Authors Ghanem, Hebah, Sivasubramanian, Geetha
Format Journal Article
LanguageEnglish
Published New York Hindawi 04.06.2021
John Wiley & Sons, Inc
Wiley
Subjects
Acquired immune deficiency syndrome
AIDS
B cells
Care and treatment
Case Report
Case reports
Coronaviruses
Corticosteroids
COVID-19
Development and progression
Encephalitis
Fungal infections
Health aspects
HIV
Human immunodeficiency virus
Immunocompetence
Medical research
Medicine, Experimental
Meningitis
T cells
China
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Summary:Cryptococcus neoformans is a saprophytic fungus that causes fatal disseminated infections in immunocompromised hosts. Since the onset of the COVID-19 pandemic, multiple cases of secondary viral, bacterial, and fungal infections have been reported in patients after SARS-CoV-2 infection. We describe here a case of severe cryptococcal meningitis that developed in a previously healthy patient one week after treatment of SARS-CoV-2 infection with dexamethasone. This case adds to the growing knowledge of emerging secondary infectious complications including opportunistic pathogens after SARS-CoV-2 infection. While few reports allude to depressed T-cell function and lymphopenia due to SARS-CoV-2 infection, further studies are needed to evaluate the effects of this infection and its treatment on the immune system and its contribution to the emergence of secondary opportunistic infections.
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Academic Editor: Mohd Adnan
ISSN:2090-6625
2090-6633
DOI:10.1155/2021/5597473