Non-Coding RNAs of Extracellular Vesicles: Key Players in Organ-Specific Metastasis and Clinical Implications

• Published in: Cancers Vol. 14; no. 22; p. 5693
• Main Authors: Jiang, Qian, Tan, Xiao-Ping, Zhang, Cai-Hua, Li, Zhi-Yuan, Li, Du, Xu, Yan, Liu, Yu Xuan, Wang, Lingzhi, Ma, Zhaowu
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.11.2022; MDPI
• Subjects: Angiogenesis; Biomarkers; Biosynthesis; Bone marrow; Cancer; Cell death; Cell interactions; Cell organelles; Communication; Development and progression; Extracellular vesicles; Gene expression; Genetic aspects; Health aspects; Liver; Lymph nodes; Membrane vesicles; Metastases; Metastasis; Non-coding RNA; Organotropism; Patients; Phenotypes; Prostate; Proteins; Review; RNA; Therapeutic applications; Therapeutic targets; Tumor cells; Tumors; China; organ-specific metastasis; anti-cancer metastasis; extracellular vesicles; cancer biomarkers; noncoding RNAs

Extracellular vesicles (EVs) are heterogeneous membrane-encapsulated vesicles released by most cells. They act as multifunctional regulators of intercellular communication by delivering bioactive molecules, including non-coding RNAs (ncRNAs). Metastasis is a major cause of cancer-related death. Most...