Eosinophilic pneumonia: A rare manifestation of amiodarone toxicity diagnosed using traditional bronchoscopy

Amiodarone is an antiarrhythmic agent used primarily to treat atrial and ventricular arrhythmias. However, the drug also has many adverse effects, including pulmonary toxicity, and a wide range of pulmonary diseases have been reported. Amiodarone-induced eosinophilic pneumonia is a relatively rare a...

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Bibliographic Details
Published inRespiratory medicine case reports Vol. 27; p. 100856
Main Authors LeVee, Alexis, Trieu, Megan, Bhattacharyya, Sarathi, Sandhu, Gurveen
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.01.2019
Elsevier
Subjects
Adverse effects
Amiodarone
Eosinophilic
Pneumonia
Toxicity
Pneumonia
Amiodarone
Adverse effects
Toxicity
Eosinophilic
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Summary:Amiodarone is an antiarrhythmic agent used primarily to treat atrial and ventricular arrhythmias. However, the drug also has many adverse effects, including pulmonary toxicity, and a wide range of pulmonary diseases have been reported. Amiodarone-induced eosinophilic pneumonia is a relatively rare adverse effect with an incidence ranging between 5 and 13% [1]. The majority of cases have been diagnosed with lung biopsy, with only one prior reported case diagnosed by bronchoalveolar lavage (BAL) [2]. This report describes the second documented case of amiodarone-induced eosinophilic pneumonia diagnosed by eosinophilia on BAL cytology. In this case, complete cessation of symptoms occurred after discontinuation of amiodarone and treatment with corticosteroids. An updated review of the literature of amiodarone-induced eosinophilic pneumonia is also detailed.
ISSN:2213-0071
2213-0071
DOI:10.1016/j.rmcr.2019.100856