Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2
To clarify the function of the receptor binding protein for inositol hexakisphosphate (IP 6), we obtained a partial amino acid sequence from the purified protein and a partial nucleotide sequence from a cDNA clone of the gene. The sequences are essentially identical to those of the α-subunit of the...
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Published in | Biochemical and biophysical research communications Vol. 187; no. 1; pp. 158 - 163 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
San Diego, CA
Elsevier Inc
31.08.1992
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | To clarify the function of the receptor binding protein for inositol hexakisphosphate (IP
6), we obtained a partial amino acid sequence from the purified protein and a partial nucleotide sequence from a cDNA clone of the gene. The sequences are essentially identical to those of the
α-subunit of the clathrin assembly protein AP-2. The IP
6 receptor protein analyzed by SDS-PAGE contains a series of subunits which are the same as those of AP-2. Antibodies to AP-2 react with the IP
6 receptor protein in immunoblot analysis. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0006-291X 1090-2104 |
DOI: | 10.1016/S0006-291X(05)81473-1 |