Genetic Analysis of 15 STR Loci in Chinese Han Population from West China

• Published in: Genomics, proteomics & bioinformatics Vol. 5; no. 1; pp. 66 - 69
• Main Authors: Deng, Ya-Jun, Yan, Jiang-Wei, Yu, Xiao-Guang, Li, Yuan-Zhe, Mu, Hao-Fang, Huang, Yan-Qing, Shi, Xiao-Tie, Sun, Wei-Min
• Format: Journal Article
• Language: English
• Published: China Elsevier Ltd 2007; Center of Forensic Science, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 101300, China%Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101300, China%Center of Forensic Science, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 101300, China; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101300, China; Elsevier
• Subjects: Alleles; Brief Report; China - ethnology; Chinese Han population; DNA typing; forensic science; Humans; Microsatellite Repeats - genetics; population genetic analysis; short tandem repeats; China; forensic science; population genetic analysis; short tandem repeats; Chinese Han population; DNA typing
• ISSN: 1672-0229; 2210-3244
• DOI: 10.1016/S1672-0229(07)60016-3

Allele frequencies for 15 short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, and FGA) were obtained from 7,636 unrelated individuals of Chinese Han population living in Qinghai and Chongqing, China. Totally 206 alleles were observed, with the corresponding allele frequencies ranging from 0.0001–0.4982. Chi-square test showed that all of the STR loci agreed with the Hardy-Weinberg equilibrium. We also compared our data with previously published population data of other ethnics or areas. The results are valuable for human identification and paternity testing in Chinese Han population.