Pre- and post-COVID-19 evaluation of antimicrobial susceptibility for healthcare-associated infections in the intensive care unit of a tertiary hospital

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 54; p. e00902021
• Main Authors: Gaspar, Gilberto Gambero, Ferreira, Lécio Rodrigues, Feliciano, Cinara Silva, Campos Júnior, Cláudio Penido, Molina, Fabiana Murad Rossin, Vendruscolo, Andrea Cristina Soares, Bradan, Giovana Marcão Araújo, Lopes, Nátali Artal Padovani, Martinez, Roberto, Bollela, Valdes Roberto
• Format: Journal Article
• Language: English; Portuguese
• Published: Sociedade Brasileira de Medicina Tropical - SBMT 01.01.2021; Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Bacterial resistance; COVID-19; Healthcare related infection; Short Communication; TROPICAL MEDICINE; COVID-19; Healthcare related infection; Bacterial resistance
• ISSN: 0037-8682; 1678-9849; 1678-9849
• DOI: 10.1590/0037-8682-0090-2021

INTRODUCTIONAntimicrobial resistance has worsened since the onset of COVID-19. METHODSThis study involved patients admitted to the adult intensive care unit (ICU) of a tertiary hospital. Pre- and post-COVID-19 data were analyzed. The healthcare-related infections (HCRIs) reported between January 2018 and January 2020 and during the pandemic between February and July 2020 were compared. RESULTSAntimicrobial resistance increased during the pandemic, especially for Klebsiella pneumoniae isolates, with a rate increase from 5% to 50% for Polymyxin B. CONCLUSIONSThe susceptibilities of the main pathogens associated with HCRIs in the ICU changed and should be considered in managing severe COVID-19.