Relationship between occupational stress and salivary sIgA and lysozyme in assembly line workers

• Published in: Chinese medical journal Vol. 121; no. 17; pp. 1741 - 1743
• Main Authors: Yu, Shan-Fa, Jiang, Kai-You, Zhou, Wen-Hui, Wang, Sheng
• Format: Journal Article
• Language: English
• Published: China Henan Provincial Institute of Occupational Medicine,Zhengzhou,Henan 450052,China%Department of Occupational and Environmental Medicine,Peking University Health Center,Beijing 100083,China 05.09.2008
• Subjects: Adult; Biomarkers; Humans; Immunoglobulin A, Secretory - analysis; Isoenzymes - analysis; Male; Occupational Diseases - diagnosis; Occupational Diseases - immunology; Saliva - enzymology; Saliva - immunology; Stress, Psychological - diagnosis; Stress, Psychological - immunology; 氢化可的松; 溶解酵素; 职业压力; salivary; slg A; cortisol; lysozyme; occupational stress
• ISSN: 0366-6999; 2542-5641
• DOI: 10.1097/00029330-200809010-00028

Anumber of studies have investigated the effects of stress on mental health and cardiovascular diseases and the relationship between stress and various components of the immune system, and they found that chronic stress is associated with suppression of a variety of immune parameters. However, acute stress is often associated with transient increases in immune activationl A few studies have also examined the slgA response to occupational stress. Zeier et al2 measured salivary slgA in air traffic controllers before and immediately after radar working sessions lasting approximately 100 minutes. Counter to the author＇s expectation, slgA was significantly elevated after the stressful work-session. Ng et al3 found slgA correlated inversely with self-reported levels of stress among nurses in Singapore. In the United States and Australia, studies on occupational stress in the nursing profession using salivary IgA as a stress indicator have also been conducted. Both studies indicated that the nurses＇ stress was significantly associated with a decreased salivary IgA secretion rates.4.5 A study has indicated salivary lysozyme as a promising marker of the effects of stress on nonspecific immunity, demonstrating a negative relation between perceived stress, as indicated by a stress score obtained by means of a questionnaire, and actual stress in the form of an undergraduate examination and salivary lysozyme levels.6 Ng et al3 have not found a relationship between salivary lysozyme levels and self-reported levels of stress among nurses in Singapore.