New functions of small nucleolar RNAs

Small nucleolar RNAs (snoRNAs) are one of the most abundant and well-studied groups of non-coding RNAs. snoRNAs are mostly engaged in processing of rRNA. However, recent data indicate that snoRNAs are also involved in other processes including regulation of alternative splicing, translation and oxid...

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Published inBiochemistry (Moscow) Vol. 78; no. 6; pp. 638 - 650
Main Authors Makarova, J. A., Ivanova, S. M., Tonevitsky, A. G., Grigoriev, A. I.
Format Journal Article
LanguageEnglish
Published Dordrecht SP MAIK Nauka/Interperiodica 01.06.2013
Springer
Springer Nature B.V
Subjects
Alternative Splicing
Animals
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Carcinogenesis - genetics
Carcinogenesis - metabolism
Genetic regulation
Humans
Life Sciences
Microbiology
MicroRNA
Molecular biology
Oncology
Oxidative Stress
Pathogenesis
Physiological aspects
Protein Biosynthesis
Review
Ribonucleic acid
RNA
RNA Precursors - metabolism
RNA, Small Nucleolar - genetics
RNA, Small Nucleolar - metabolism
Russia
noncoding RNA
sdRNA
oncogenesis
scaRNA
miRNA
RNA silencing
snoRNA
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Summary:Small nucleolar RNAs (snoRNAs) are one of the most abundant and well-studied groups of non-coding RNAs. snoRNAs are mostly engaged in processing of rRNA. However, recent data indicate that snoRNAs are also involved in other processes including regulation of alternative splicing, translation and oxidative stress. snoRNAs are also involved in pathogenesis of some hereditary diseases and cancer. Therefore, the range of snoRNAs’ functions is significantly wider than it has been assumed earlier.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0006-2979
1608-3040
DOI:10.1134/S0006297913060096