RANK Overexpression in Transgenic Mice with Mouse Mammary Tumor Virus Promoter-Controlled RANK Increases Proliferation and Impairs Alveolar Differentiation in the Mammary Epithelia and Disrupts Lumen Formation in Cultured Epithelial Acini

• Published in: Molecular and Cellular Biology Vol. 27; no. 4; pp. 1442 - 1454
• Main Authors: Gonzalez-Suarez, Eva, Branstetter, Daniel, Armstrong, Allison, Dinh, Huyen, Blumberg, Hal, Dougall, William C.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.02.2007; Taylor & Francis
• Subjects: Animals; Caseins - genetics; Cell Differentiation - drug effects; Cell Proliferation - drug effects; Cell Survival - drug effects; Cells, Cultured; Epithelial Cells - cytology; Epithelial Cells - drug effects; Epithelium - drug effects; Female; Gene Expression - drug effects; Gene Expression Regulation - drug effects; Mammary Glands, Animal - cytology; Mammary Glands, Animal - drug effects; Mammary Glands, Animal - growth & development; Mammary Tumor Virus, Mouse - genetics; Mice; Mice, Transgenic; Milk Proteins - genetics; Mouse mammary tumor virus; Pregnancy; Promoter Regions, Genetic - drug effects; Promoter Regions, Genetic - genetics; RANK Ligand - genetics; RANK Ligand - pharmacology; Receptor Activator of Nuclear Factor-kappa B - genetics; Receptor Activator of Nuclear Factor-kappa B - metabolism; RNA, Messenger - genetics; RNA, Messenger - metabolism; Time Factors; Transcription Factor RelA - metabolism
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.01298-06

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