Deficient median nerve prepulse inhibition of the blink reflex in cervical dystonia

Highlights • Patients with cervical dystonia have less prepulse R2 inhibition than healthy subjects. • The absence of a sensory trick leads to the more pronounced reduction of prepulse R2 inhibition. • The modulatory effects of sensory inputs are lost in the absence of a sensory trick.

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Bibliographic Details
Published inClinical neurophysiology Vol. 127; no. 12; pp. 3524 - 3528
Main Authors Öztürk, Oya, Gündüz, Ayşegül, Kızıltan, Meral E
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.12.2016
Subjects
Adult
Blink reflex
Blinking - physiology
Cervical dystonia
Electric Stimulation - methods
Female
Humans
Male
Median Nerve - physiopathology
Middle Aged
Neurology
Prepulse inhibition
Prepulse Inhibition - physiology
Sensory trick
Torticollis - diagnosis
Torticollis - physiopathology
CD
magnetic resonance imaging
MRI
pedunculopontine tegmental nucleus
PPI
cervical dystonia
prepulse inhibition
Blink reflex
STN
TWSTRS
BR
subthalamic nucleus
ISI
interstimulus interval
Toronto Western Spasmodic Torticollis Rating Scale
sensory trick
PPTN
Sensory trick
Cervical dystonia
Prepulse inhibition
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Summary:Highlights • Patients with cervical dystonia have less prepulse R2 inhibition than healthy subjects. • The absence of a sensory trick leads to the more pronounced reduction of prepulse R2 inhibition. • The modulatory effects of sensory inputs are lost in the absence of a sensory trick.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2016.09.013