Update on Coronavirus 2019 Vaccine Guidelines for Transplant Recipients

• Published in: Transplantation proceedings Vol. 54; no. 6; pp. 1399 - 1404
• Main Authors: Kute, Vivek, Meshram, Hari Shankar, Sharma, Ashish, Chaudhury, Arpita Ray, Sudhindran, S., Gokhale, AllaGopala Krishna, Hote, Milind, Guleria, Randeep, Rana, Devinder Singh, Prakash, Jai, Ramesh, Vasanthi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2022
• Subjects: Coronavirus; COVID-19 - prevention & control; Humans; Living Donors - psychology; Organ Transplantation - adverse effects; Transplant Recipients; Vaccination - adverse effects
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2021.09.007

The coronavirus disease 2019 (COVID-19) vaccine and its utility in solid organ transplantation need to be timely revised and updated. These guidelines have been formalized by the experts—the apex technical committee members of the National Organ and Tissue Transplant Organization and the heads of transplant societies—for the guidance of transplant communities. We recommend that all personnel involved in organ transplantation should be vaccinated as early as possible and continue COVID-19–appropriate behavior despite a full course of vaccination. For specific guidelines of recipients, we suggest completing the full schedule before transplantation whenever the clinical condition permits. We also suggest a single dose, rather than proceeding unvaccinated for transplant, in case a complete course is not feasible. If vaccination is planned before surgery, we recommend a gap of at least 2 weeks between the last dose of vaccine and surgery. For those not vaccinated before transplant, we suggest waiting 4 to 12 weeks after transplant. For the potential living donors, we recommend the complete vaccination schedule before transplant. However, if this is not feasible, we suggest receiving at least a single dose of the vaccine 2 weeks before donation. We suggest that suitable transplant patients and those on the waiting list should accept a third dose of the vaccine when one is offered to them. We recommend that organs from a deceased donor with suspected/proven vaccine-induced thrombotic thrombocytopenia should be avoided and are justified only in cases of emergency situations with informed consent and counseling.