Antiviral activity of porcine interferon omega 7 against foot‐and‐mouth disease virus in vitro

• Published in: Journal of medical virology Vol. 91; no. 2; pp. 208 - 214
• Main Authors: Li, Shi‐Fang, Zhao, Fu‐Rong, Gong, Mei‐Jiao, Shao, Jun‐Jun, Xie, Yin‐Li, Chang, Hui‐Yun, Zhang, Yong‐Guang
• Format: Journal Article Web Resource
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2019; John Wiley & Sons; John Wiley and Sons Inc
• Subjects: Animals; Antiviral activity; Antiviral Agents - pharmacology; Antiviral drugs; Cell proliferation; Chemical compounds; Cytopathogenic Effect, Viral; E coli; Economic importance; Foot & mouth disease; foot-and-mouth disease virus (FMDV; Foot-and-Mouth Disease Virus - drug effects; Foot-and-Mouth Disease Virus - growth & development; Fusion protein; Genes; Infections; Interferon; interferon stimulated genes (ISG); Interferon Type I - genetics; Interferon Type I - pharmacology; Life sciences; Livestock; Microbiologie; Microbiology; Myxovirus resistance proteins; nterferon stimulated genes (ISG); Outbreaks; Pharmacology; Polymerase chain reaction; porcine IFN omega 7 (PoIFN‐ω7); Proteins; Recombinant Fusion Proteins - genetics; Recombinant Fusion Proteins - pharmacology; Sciences du vivant; Swine; Transcription; type I interferon; Vaccines; Virology; Viruses; type I interferon; porcine IFN omega 7 (PoIFN-ω7); antiviral activity; foot-and-mouth disease virus (FMDV); interferon stimulated genes (ISG)

Foot‐and‐mouth disease (FMD) is a disease of worldwide economic importance, and vaccines play an important role in preventing FMDV outbreaks. However, new control strategies are still needed since FMDV outbreaks still occur in some disease‐free countries. Currently, interferon (IFN)‐based strategies...