Human papillomavirus typing and soluble interleukin-2 receptor levels in female sex workers with a negative cervical smear result
Abstract Objective To investigate the association between high-risk human papillomavirus (HPV) types and soluble interleukin-2 receptor (sIL-2R) levels in female sex workers with a negative cervical smear result, and to determine the effectiveness of using sIL-2R levels to screen for high-risk strai...
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Published in | International journal of gynecology and obstetrics Vol. 106; no. 3; pp. 210 - 212 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Shannon
Elsevier Ireland Ltd
01.09.2009
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Abstract Objective To investigate the association between high-risk human papillomavirus (HPV) types and soluble interleukin-2 receptor (sIL-2R) levels in female sex workers with a negative cervical smear result, and to determine the effectiveness of using sIL-2R levels to screen for high-risk strains of HPV. Method A negative cervical smear result and a blood sample were obtained from 68 women: 43 female sex workers and 25 women acting as controls. HPV DNA genotyping was performed and sIL-2R levels were assessed. Results Female sex workers had significantly higher sIL-2R levels than women in the control group (318.37 ± 239.7 vs 114.4 ± 56.5 U/mL, respectively P < 0.001). In addition, female sex workers with high-risk strains of HPV had significantly higher sIL-2R levels than those who did not have high-risk strains of HPV (736.7 ± 251.5 vs 250.5 ± 156.1 U/mL, respectively; P = 0.001). Conclusion High sIL-2R levels may be useful in screening for high-risk strains of HPV in female sex workers who have a negative cervical smear result. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0020-7292 1879-3479 |
DOI: | 10.1016/j.ijgo.2009.04.005 |