Vitamin D status in children with Crimean-Congo hemorrhagic fever

• Published in: Journal of vector borne diseases Vol. 52; no. 1; pp. 36 - 39
• Main Authors: Uysal, E B, Tuzcu, N, Sancakdar, E, Güven, A S, Akkar, I, Deveci, K, Kaya, A
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 2015; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: Adolescent; Antimicrobial agents; Blood; Calcium - blood; Child; Child, Preschool; Crimean hemorrhagic fever; Ear diseases; Hemorrhagic Fever Virus, Crimean-Congo - genetics; Hemorrhagic Fever Virus, Crimean-Congo - isolation & purification; Hemorrhagic Fever, Crimean - diagnosis; Hemorrhagic Fever, Crimean - metabolism; Humans; Infections; Measurement; Metabolism; Metabolites; Mortality; Older people; Parathyroid Hormone - blood; Patients; Pediatric diseases; Pediatrics; Physiological aspects; Real-Time Polymerase Chain Reaction; Studies; Tonsillitis; Tuberculosis; Values; Vitamin D; Vitamin D - blood; Vitamin deficiency; Turkey
• ISSN: 0972-9062
• DOI: 10.4103/0972-9062.154147

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease, causing severe viral hemorrhagic fever outbreaks. This study aimed at determining the serum vitamin D levels and investigated the association between Crimean-Congo hemorrhagic fever (CCHF) and serum vitamin D levels in children with CCHF. A total of 45 children aged between 5 and 15 yr, viz. 15 healthy control (HC) and 30 pediatric patients diagnosed with CCHF with real-time polymerase chain reaction (PCR) (patient group) were selected for the study. Analysis of the blood serum samples taken from the said individuals revealed that vitamin D, parathyroid hormone and calcium levels of the patients and the control groups were statistically different. It was found that the serum vitamin D levels of the pediatric patients with CCHF were lower when compared to those of the controls, and that a low vitamin D level could negatively affect the reaction of the body to infections in children having CCHF.