Antibacterial ent-kaurene from Brazilian propolis of native stingless bees

Three ent-kaurene diterpenoids, not previously described as constituents of propolis, were isolated from a sample collected by Brazilian native bees Melipona quadrifasciata anthidioides. One of them, kaurenoic acid, as well as the total extract, displayed moderate antibacterial activity.

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Bibliographic Details
Published inFitoterapia Vol. 71; no. 6; pp. 693 - 696
Main Authors Velikova, M, Bankova, V, Tsvetkova, I, Kujumgiev, A, Marcucci, M.C
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 01.12.2000
Elsevier
Subjects
Animals
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - pharmacology
Antibacterial activity
Apidae
Bees
Biological and medical sciences
Brazil
Diterpenes - isolation & purification
Diterpenes - pharmacology
diterpenoids
ent-Kaurene diterpenoids
Escherichia coli - drug effects
General pharmacology
Humans
kaurenoic acid
Medical sciences
Melipona quadrifasciata
Melipona quadrifasciata anthidioides
Microbial Sensitivity Tests
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Propolis
Propolis - chemistry
Staphylococcus aureus - drug effects
South America
Brazil
America
Antibacterial activity
ent-Kaurene diterpenoids
Melipona quadrifasciata anthidioides
Propolis
Terpenoid
Insecta
Apis
Apidae
Animal origin
In vitro
Biological activity
Apoidea
Arthropoda
Diterpene
Hymenoptera
Invertebrata
Antibacterial agent
Aculeata
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Summary:Three ent-kaurene diterpenoids, not previously described as constituents of propolis, were isolated from a sample collected by Brazilian native bees Melipona quadrifasciata anthidioides. One of them, kaurenoic acid, as well as the total extract, displayed moderate antibacterial activity.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0367-326X
DOI:10.1016/S0367-326X(00)00213-6