Correlation Among Lens Opacities Classification System III Grading, Visual Function Index-14, Pentacam Nucleus Staging, and Objective Scatter Index for Cataract Assessment

• Published in: American journal of ophthalmology Vol. 159; no. 2; pp. 241 - 247.e2
• Main Authors: Pan, An-Peng, Wang, Qin-Mei, Huang, Fang, Huang, Jin-Hai, Bao, Fang-Jun, Yu, A-Yong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2015; Elsevier Limited
• Subjects: Adult; Aged; Aged, 80 and over; Blindness; Cataract - classification; Cataract - diagnosis; Cataract - physiopathology; Cataracts; Classification; Cross-Sectional Studies; Eye surgery; Female; Health risk assessment; Hospitals; Humans; Lens Nucleus, Crystalline - pathology; Light; Male; Methods; Middle Aged; Ophthalmology; Patients; Photography - methods; Prospective Studies; Quality standards; Scattering, Radiation; Sickness Impact Profile; Software; Statistics as Topic; Studies; Surgery; Surveys and Questionnaires; Visual Acuity - physiology; China
• ISSN: 0002-9394; 1879-1891; 1879-1891
• DOI: 10.1016/j.ajo.2014.10.025

To investigate the relationship among Lens Opacities Classification System III (LOCS III) grading score, Visual Function Index-14 (VF-14) score, average lens density by the Pentacam Nucleus Staging system, and the objective scatter index measured by the Optical Quality Analysis System in age-related cataract patients. Prospective, single-center, cross-sectional study. Thirty-six subjects (60 eyes) with age-related cataract were recruited. Subjects with any corneal anomaly potentially affecting intraocular scatter were excluded. The best-corrected visual acuity (BCVA), LOCS III nuclear opalescence score and cortical cataract score, VF-14 score, average lens density, and objective scatter index were obtained. Correlations among these parameters were analyzed. The LOCS III nuclear opalescence score was correlated with the BCVA (r = 0.438; P = .001), objective scatter index (r = 0.543; P < .001), and average lens density (r = 0.621; P < .001). The objective scatter index was also correlated with the BCVA (r = 0.779; P < .001) and the average lens density (r = 0.320; P = .013). The VF-14 score had the strongest correlation with the objective scatter index (r = −0.712; P < .001). The difference between groups with objective scatter index<3.0 and ≥3.0 was significant with regard to BCVA, average lens density, LOCS III nuclear opalescence score, and VF-14 score. LOCS III grading remains an economical and effective method to assess lens opacities, especially in the formation of early cortex cataracts. The objective scatter index can be a useful parameter to objectively analyze the correlation between ocular examination findings and patient concerns. Furthermore, the objective scatter index scores ≥3.0 can be a possible objective cut-off for preoperative decision making.