The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

This review intends to provide the reader with a practical overview of several (patho)physiological conditions in which knowledge of the interplay between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and insulin is important. This might help treating physicians in making the right deci...

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Published inEndocrinology and metabolism (Seoul) Vol. 39; no. 1; pp. 83 - 89
Main Authors Nijenhuis-Noort, Eline C, Berk, Kirsten A, Neggers, Sebastian J C M M, Lely, Aart J van der
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Endocrine Society 01.02.2024
대한내분비학회
Subjects
acromegaly
diabetes mellitus, type 1
diabetes mellitus, type 2
growth hormone
humans
insulin
insulin, human
insulin-like growth factor i
liver cirrhosis
Review
내과학
Diabetes mellitus, type 2
Insulin-like growth factor I
Humans
Diabetes mellitus, type 1
Acromegaly
Growth hormone
Insulin
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Summary:This review intends to provide the reader with a practical overview of several (patho)physiological conditions in which knowledge of the interplay between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and insulin is important. This might help treating physicians in making the right decisions on how to intervene and improve metabolism for the benefit of patients, and to understand why and how metabolism responds in their specific cases. We will specifically address the interplay between GH, IGF-1, and insulin in type 1 and 2 diabetes mellitus, liver cirrhosis, and acromegaly as examples in which this knowledge is truly necessary.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2093-596X
2093-5978
DOI:10.3803/EnM.2024.101