Non-coding RNAs as direct and indirect modulators of epigenetic regulation

• Published in: Epigenetics Vol. 9; no. 1; pp. 3 - 12
• Main Authors: Peschansky, Veronica J, Wahlestedt, Claes
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.01.2014; Landes Bioscience
• Subjects: chromatin; DNA Methylation - genetics; DNA Modification Methylases - genetics; DNA Modification Methylases - metabolism; Epigenesis, Genetic; epigenetics; gene expression; Gene Silencing; histone; Histones - genetics; Histones - metabolism; Humans; lncRNA; microRNA; noncoding RNA; piRNA; polycomb; Polycomb-Group Proteins - genetics; Polycomb-Group Proteins - metabolism; Review; RNA, Untranslated - classification; RNA, Untranslated - genetics; RNA, Untranslated - metabolism; lncRNA; noncoding RNA; piRNA; polycomb; microRNA; histone; chromatin; epigenetics; gene expression

Epigenetic regulation of gene expression is an increasingly well-understood concept that explains much of the contribution of an organism's environment and experience to its biology. However, discussion persists as to which mechanisms can be classified as epigenetic. Ongoing research continues...