Quinidine-induced reversible pneumonitis

We report a patient who developed fever and rapidly progressing lung infiltrates 4 days after the beginning of continuous quinidine sulfate therapy. The fever disappeared during the following 48 h and the pneumonitis slowly resolved over the next month once quinidine therapy was stopped. The diagnos...

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Bibliographic Details
Published inChest Vol. 106; no. 1; p. 304
Main Authors Poukkula, A, Pääkkö, P
Format Journal Article
LanguageEnglish
Published United States 01.07.1994
Subjects
Humans
Lung - diagnostic imaging
Lung - pathology
Male
Middle Aged
Pneumonia - chemically induced
Pneumonia - diagnostic imaging
Pneumonia - pathology
Quinidine - adverse effects
Radiography
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Summary:We report a patient who developed fever and rapidly progressing lung infiltrates 4 days after the beginning of continuous quinidine sulfate therapy. The fever disappeared during the following 48 h and the pneumonitis slowly resolved over the next month once quinidine therapy was stopped. The diagnosis of quinidine-induced pneumonitis, which has not previously been reported in the literature (to our knowledge), was confirmed by means of a rechallenge with quinidine.
ISSN:0012-3692
DOI:10.1378/chest.106.1.304