Retinal measurements using time domain OCT imaging before and after myopic Lasik

• Published in: Ophthalmic & physiological optics Vol. 32; no. 3; pp. 222 - 227
• Main Authors: Lei, Feng, Burns, Stephen A, Shao, Liqin, Yang, Yabo
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.05.2012; Blackwell
• Subjects: Adolescent; Adult; Biological and medical sciences; Biometry; Cornea - pathology; Corneal Topography - methods; Eye and associated structures. Visual pathways and centers. Vision; Female; Fundamental and applied biological sciences. Psychology; Humans; Intraocular Pressure - physiology; Keratomileusis, Laser In Situ - methods; laser in situ keratomileusis; Macula Lutea - pathology; macular volume; Male; Medical sciences; Myopia - pathology; Myopia - physiopathology; Myopia - surgery; Ophthalmology; optical coherence tomography; Postoperative Period; Preoperative Period; Refraction, Ocular; retina; Retina - pathology; Tomography, Optical Coherence - methods; Vertebrates: nervous system and sense organs; Vision disorders; Young Adult; Measurement; Postoperative; Keratomileusis; Optical coherence tomography; Vision disorder; In situ; Myopia; Retina; macular volume; Macula; Eye disease; Treatment; Volume; Surgery; Refractive error; Laser; laser in situ keratomileusis; Ophthalmology
• ISSN: 0275-5408; 1475-1313
• DOI: 10.1111/j.1475-1313.2012.00905.x

Citation information: Lei F, Burns SA, Shao L & Yang Y. Retinal measurements using time domain OCT imaging before and after myopic Lasik. Ophthalmic Physiol Opt 2012, 32, 222–227. doi: 10.1111/j.1475‐1313.2012.00905.x Purpose:  To compare retinal measurements obtained by time domain optical coherence tomography (OCT) devices before and after myopic laser in situ keratomileusis (Lasik) and to assess the interaction of Lasik and retinal structures as measured by time domain OCT. Methods:  Fifty‐three patients randomly selected participated in the study. Only the right eye of each subject was included in the study. Comprehensive ophthalmic examinations including refraction examination, slit lamp examination, dilated fundus examination, corneal topography, corneal thickness, intraocular pressure, and retinal Stratus OCT scans were acquired for each patient before myopic Lasik and 3 months after surgery. Results:  Total macular volume (TMV) changed significantly between preoperative and postoperative measurements (p = 0.003). No statistical differences were found between preoperative and postoperative disc area, rim area, cup/disk vert. ratio, or average foveal thickness (p > 0.05). The variation in TMV correlated significantly with the change in spherical refraction equivalent, maximal corneal curvature, minimal corneal curvature, and corneal ablation depth. Conclusions:  Most retinal OCT measurements undergo no obvious changes after myopic Lasik. The increased TMV measurements we measured after Lasik seem to be correlated with the alteration in corneal shape. The exact mechanism for this change is not clear, while we examined several possibilities including subclinical macular oedema, magnification changes, errors in OCT analysis and IOP, none of these seem to be a likely cause.