The effects of fasting plasma glucose variability and time-dependent glycemic control on the long-term risk of retinopathy in type 2 diabetic patients

Abstract Long-term fasting plasma glucose (FPG) variability was a risk factor for proliferative diabetic retinopathy (PDR) independent of the mean FPG or HbA1c in people with type 2 diabetes. PDR development was also significantly associated with mean HbA1c more than 5 years earlier and with mean FP...

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Published inDiabetes research and clinical practice Vol. 91; no. 2; pp. e40 - e42
Main Authors Takao, Toshiko, Ide, Takehiko, Yanagisawa, Hiroyuki, Kikuchi, Masatoshi, Kawazu, Shoji, Matsuyama, Yutaka
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.02.2011
Subjects
Adult
Blood Glucose - metabolism
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - metabolism
Diabetic Retinopathy - blood
Diabetic Retinopathy - etiology
Diabetic Retinopathy - metabolism
Endocrinology & Metabolism
Fasting - blood
Female
Glucose variability
Glycated Hemoglobin A
Humans
Long-term
Male
Retinopathy
Risk Factors
Time Factors
Time-dependent glycemic control
Type 2 diabetes
Type 2 diabetes
Glucose variability
Long-term
Retinopathy
Time-dependent glycemic control
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Summary:Abstract Long-term fasting plasma glucose (FPG) variability was a risk factor for proliferative diabetic retinopathy (PDR) independent of the mean FPG or HbA1c in people with type 2 diabetes. PDR development was also significantly associated with mean HbA1c more than 5 years earlier and with mean FPG more than 10 years earlier.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2010.10.009