Nanoscale assembly of amine-functionalized colloidal iron oxide

• Published in: Journal of magnetism and magnetic materials Vol. 321; no. 10; pp. 1529 - 1532
• Main Authors: Barick, K.C., Aslam, M., Prasad, Pottumarthi V., Dravid, Vinayak P., Bahadur, Dhirendra
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier B.V 01.05.2009; Elsevier
• Subjects: Biological and medical sciences; Cross-disciplinary physics: materials science; rheology; Exact sciences and technology; Iron oxide; Materials science; Medical sciences; MR contrast agent; Nanoassembly; Nanoparticle; Nanopowders; Nanoscale materials and structures: fabrication and characterization; Physics; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Surface functionalization; Technology. Biomaterials. Equipments. Material. Instrumentation; Surface functionalization; Iron oxide; Nanoassembly; Nanoparticle; MR contrast agent; Thermal decomposition; Spin echo; Nuclear magnetic resonance imaging; Chemical modification; Amine; Fourier-transformed infrared spectrometry; Saturation magnetization; Organic compounds
• ISSN: 0304-8853
• DOI: 10.1016/j.jmmm.2009.02.080

We demonstrate a single-step facile approach for highly water-stable assembly of amine-functionalized Fe 3O 4 nanoparticles using thermal decomposition of Fe-chloride precursors in ethylene glycol medium in the presence of ethylenediamine. The average size of nanoassemblies is 40±1 nm, wherein the individual nanoparticles are about 6 nm. Amine-functionalized properties are evident from Fourier transform infrared spectrometer (FTIR), thermal and elemental analyses. The saturation magnetization and spin-echo r 2 of the nanoassemblies were measured to be 64.3 emu/g and 314.6 mM −1 s −1, respectively. The higher value of relaxivity ratio ( r 2/ r 1=143) indicates that nanoassemblies are a promising high-efficiency T2 contrast agent platform.