Micromilling: a method for ultra-rapid prototyping of plastic microfluidic devices

This tutorial review offers protocols, tips, insight, and considerations for practitioners interested in using micromilling to create microfluidic devices. The objective is to provide a potential user with information to guide them on whether micromilling would fill a specific need within their over...

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Bibliographic Details
Published inLab on a chip Vol. 15; no. 11; pp. 2364 - 2378
Main Authors Guckenberger, David J, de Groot, Theodorus E, Wan, Alwin M D, Beebe, David J, Young, Edmond W K
Format Journal Article
LanguageEnglish
Published England 07.06.2015
Subjects
Equipment Design - methods
Microfluidic Analytical Techniques - instrumentation
Microtechnology - methods
Plastics
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Summary:This tutorial review offers protocols, tips, insight, and considerations for practitioners interested in using micromilling to create microfluidic devices. The objective is to provide a potential user with information to guide them on whether micromilling would fill a specific need within their overall fabrication strategy. Comparisons are made between micromilling and other common fabrication methods for plastics in terms of technical capabilities and cost. The main discussion focuses on "how-to" aspects of micromilling, to enable a user to select proper equipment and tools, and obtain usable microfluidic parts with minimal start-up time and effort. The supplementary information provides more extensive discussion on CNC mill setup, alignment, and programming. We aim to reach an audience with minimal prior experience in milling, but with strong interests in fabrication of microfluidic devices.
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ISSN:1473-0197
1473-0189
DOI:10.1039/c5lc00234f