NPM1-mutated acute myeloid leukaemia occurring in JAK2-V617F+ primary myelofibrosis : de-novo origin?

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Bibliographic Details
Published inLeukemia Vol. 22; no. 7; pp. 1459 - 1463
Main Authors PASQUALUCCI, L, LI, S, HAFERLACH, T, SKODA, R. C, FALINI, B, MELONI, G, SCHNITTGER, S, GATTENLOHNER, S, LISO, A, DI IANNI, M, MARTELLI, M. P, PESCARMONA, E, FOA, R
Format Journal Article
LanguageEnglish
Published London Nature Publishing 01.07.2008
Nature Publishing Group
Subjects
Acute myeloid leukemia
Biological and medical sciences
Case studies
Cellular proteins
Complications and side effects
Diagnosis
Female
Gene mutations
Genetic aspects
Health aspects
Hematologic and hematopoietic diseases
Humans
Janus kinase 2
Janus Kinase 2 - genetics
Leukemia
Leukemia, Myeloid, Acute - genetics
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Middle Aged
Mutation
Myelofibrosis
Nuclear Proteins - genetics
Primary Myelofibrosis - genetics
Risk factors
X Chromosome Inactivation
Germany
Acute myelogenous leukemia
Myelofibrosis
Hematology
Enzyme
JAK2 protein tyrosine kinase
Transferases
NPM1 gene
Malignant hemopathy
De novo
Myeloproliferative syndrome
Mutation
Protein-tyrosine kinase
Cancer
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ISSN:0887-6924
1476-5551
DOI:10.1038/sj.leu.2405093