Correlation of preclinical and clinical biomarkers with efficacy and toxicity of cancer immunotherapy

• Published in: Therapeutic Advances in Medical Oncology Vol. 15; p. 17588359231163807
• Main Authors: Zheng, Lin-Peng, Yang, Jing, Chen, Xie-Wan, Li, Ling-Chen, Sun, Jian-Guo
• Format: Book Review Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2023; Sage Publications Ltd; SAGE Publishing
• Subjects: Artificial intelligence; Biomarkers; Cancer; Cancer immunotherapy; Genomic Biomarkers in Cancer Immunotherapy; Immune checkpoint inhibitors; Malignancy; Patients; Peripheral blood; Solid tumors; Toxicity; Tumor microenvironment; pseudoprogression; immune checkpoint inhibitors; biomarker; immune-related adverse events; hyperprogressive disease

Immune checkpoint inhibitors (ICIs) have revealed significant clinical values in different solid tumors and hematological malignancy, changing the landscape for the treatment of multiple types of cancer. However, only a subpopulation of patients has obvious tumor response and long-term survival afte...