Potassium iodide in dermatology: A 19th century drug for the 21st century—uses, pharmacology, adverse effects, and contraindications

Potassium iodide (KI) is a useful drug in the dermatologic armamentarium. It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for...

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Published inJournal of the American Academy of Dermatology Vol. 43; no. 4; pp. 691 - 697
Main Authors Sterling, J.Barton, Heymann, Warren R.
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 01.10.2000
Elsevier
Subjects
Biological and medical sciences
Humans
Medical sciences
Pharmacology. Drug treatments
Potassium Iodide - pharmacology
Potassium Iodide - therapeutic use
Skin Diseases - drug therapy
Skin, nail, hair, dermoskeleton
Thyroid Gland - drug effects
Thyroid Gland - metabolism
Human
Counter indication
Skin disease
Indication
Toxicity
Pharmacology
Review
Potassium iodide
Mechanism of action
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Summary:Potassium iodide (KI) is a useful drug in the dermatologic armamentarium. It is successfully used for inflammatory dermatoses, most notably erythema nodosum, subacute nodular migratory panniculitis, nodular vasculitis, erythema multiforme, and Sweet's syndrome. KI is also successfully used for cutaneous and lymphocutaneous sporotrichosis. The precise mechanism by which KI acts is unknown. Although many minor side effects are common with this drug, major side effects can occur in pregnant patients and those with a history of kidney or thyroid disease. This article reviews the pharmacology, mechanism of action, indications, contraindications, and adverse effects of KI as a therapeutic agent. (J Am Acad Dermatol 2000;43:691-7.)
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ISSN:0190-9622
1097-6787
DOI:10.1067/mjd.2000.107247