Clinical analysis of secondary glaucoma in Central China

• Published in: Scientific reports Vol. 13; no. 1; pp. 8439 - 9
• Main Authors: Liu, Qian, Liu, Changgeng, Cheng, Wenjun, Feng, Xiaomei, Li, Haijun, Yang, Xiaoyuan, Dong, Yangzeng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.05.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/308; 692/699/3161; Acuity; Adult; Aged; At risk populations; Coronaviruses; COVID-19; COVID-19 - epidemiology; Education; Epidemiology; Female; Follow-Up Studies; Glaucoma; Glaucoma - epidemiology; Glaucoma - surgery; Glaucoma Drainage Implants; Humanities and Social Sciences; Humans; Intraocular Pressure; Male; Middle Aged; multidisciplinary; Pandemics; Patients; Prosthesis Implantation; Retrospective Studies; Science; Science (multidisciplinary); Trauma; Treatment Outcome; Vascular diseases; Vascularization; China
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-34872-8

To describe the epidemiology, clinical and social characteristics, management, and outcomes of patients with secondary glaucoma in Central China, a total of 1,129 cases (1,158 eyes) among 710 males (62.89%) and 419 females (37.11%) were analyzed. The mean age was 53.75 ± 17.11 years. The New Rural Cooperative Medical System (NCMS) played the most important role in reimbursement (60.32%) for secondary glaucoma-related medical expenses. The predominant occupation was “farmer” (53.41%). Neovascularization and trauma were the leading causes of secondary glaucoma. Cases of trauma-induced glaucoma decreased substantially during the coronavirus disease 2019 (COVID-19) pandemic. An education level of senior high school or above was uncommon. Ahmed glaucoma valve implantation was the most commonly performed surgery. At the final follow-up, the overall intraocular pressure (IOP) in patients with vascular disease- and trauma-related secondary glaucoma was 19.53 ± 10.20 mmHg, 20.26 ± 11.75 mmHg, and 16.90 ± 6.72 mmHg, while the mean visual acuity (VA) was 0.33 ± 0.32, 0.34 ± 0.36, and 0.43 ± 0.36. In 814 (70.29%) eyes, the VA was < 0.01. Effective preventive measures for at-risk populations, increased NCMS coverage and the promotion of higher education are necessary. These findings will help ophthalmologists detect secondary glaucoma early and manage it in a timely manner.