Comparison of various methods for quantification of apparent diffusion coefficient of head and neck lesions with HASTE diffusion-weighted MR imaging

Objectives The purposes of this retrospective study were to compare various methods of apparent diffusion coefficient (ADC) measurement for head and neck lesions in half-Fourier single-shot turbo spin-echo (HASTE) diffusion-weighted imaging (DWI) and determine the threshold ADC value for predicting...

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Published inOral surgery, oral medicine, oral pathology and oral radiology Vol. 114; no. 2; pp. 266 - 276
Main Authors Sakamoto, Junichiro, DDS, PhD, Sasaki, Yoshinori, DDS, Otonari-Yamamoto, Mika, DDS, PhD, Sano, Tsukasa, DDS, PhD
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 01.08.2012
Elsevier
Subjects
Adult
Aged
Analysis of Variance
Biological and medical sciences
Cysts - pathology
Dentistry
Diffusion Magnetic Resonance Imaging - methods
Echo-Planar Imaging - methods
Female
Fourier Analysis
Head and Neck Neoplasms - pathology
Humans
Image Enhancement - methods
Linear Models
Male
Medical sciences
Middle Aged
Otorhinolaryngology. Stomatology
Retrospective Studies
ROC Curve
Statistics, Nonparametric
Surgery
Young Adult
Head and neck
Medical imagery
Lesion
Diffusion coefficient
Nuclear magnetic resonance imaging
Comparative study
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Summary:Objectives The purposes of this retrospective study were to compare various methods of apparent diffusion coefficient (ADC) measurement for head and neck lesions in half-Fourier single-shot turbo spin-echo (HASTE) diffusion-weighted imaging (DWI) and determine the threshold ADC value for predicting malignancy. Study Design HASTE DW images of 46 lesions (10 cysts, 14 benign tumors, and 22 malignant tumors) were studied retrospectively. The ADC values were compared among the 0-1000 method, 500-1000 method, and weighted linear regression (WLR) fit. Results The highest overall accuracies of 83.3%, 86.1%, and 88.9% were obtained when ADC values of 1.24 × 10−3 mm2 /s (0-1000 method), 0.98 × 10−3 mm2 /s (500-1000 method), and 1.23 × 10−3 mm2 /s (WLR fit), respectively, were used for the threshold. Conclusions The present results indicate that ADC measurement with HASTE DWI is useful in predicting malignancy of head and neck lesions.
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ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2012.03.015