Effects of temperature and humidity on cerebrovascular disease hospitalization in a super-aging society

• Published in: Scientific reports Vol. 13; no. 1; p. 20602
• Main Authors: Doi, Shunichi, Yoneyama, Kihei, Yoshida, Toshiya, Kawagoe, Yasuhito, Nakai, Michikazu, Sumita, Yoko, Ishibashi, Yuki, Izumo, Masaki, Tanabe, Yasuhiro, Harada, Tomoo, Akashi, Yoshihiro J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.11.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/499; 692/617; 692/700; 704/844; Aging; Air pollution; Cardiovascular diseases; Cerebrovascular disease; Cerebrovascular diseases; Cerebrovascular Disorders - epidemiology; Hospitalization; Humanities and Social Sciences; Humans; Humidity; multidisciplinary; Patients; Regression analysis; Science; Science (multidisciplinary); Temperature; Temperature effects; Weather
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-47998-6

Weather conditions influence the incidence of cardiovascular disease. However, few studies have investigated the association between weather temperature and humidity and cerebrovascular disease hospitalizations in a super-aging society. We included 606,807 consecutive patients with cerebrovascular disease admitted to Japanese acute-care hospitals between 2015 and 2019. The primary outcome was the number of cerebrovascular disease hospitalizations per day. Multilevel mixed-effects linear regression models were used to estimate the association of mean temperature and humidity, 1 day before hospital admission, with cerebrovascular disease hospitalizations, after adjusting for air pollution, hospital, and patient demographics. Lower mean temperatures and humidity < 70% or humidity ≧ 70% are associated with an increased incidence of cerebrovascular disease hospitalization (coefficient, − 1.442 [− 1.473 to − 1.411] per °C, p  < 0.001, coefficient, − 0.084 [− 0.112 to − 0.056] per%, p  < 0.001, and coefficient, 0.136 [0.103 to 0.168] per %, p  < 0.001, respectively). Lower mean temperatures and extremely lower or higher humidity are associated with an increased incidence of cerebrovascular disease hospitalization in a super-aging society.