Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09
We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. I...
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Published in | Emerging infectious diseases Vol. 30; no. 1; pp. 168 - 171 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
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United States
Centers for Disease Control and Prevention
01.01.2024
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Abstract | We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated. |
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AbstractList | We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated. We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated.We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated. |
Author | Luk, Leo L.H. Daulagala, Pavithra Leung, Kathy Yen, Hui-Ling Peiris, Malik Wu, Joseph T. Chin, Alex Poon, Leo L.M. Cheng, Samuel M.S. |
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Keywords | clade 2.3.4.4.b influenza influenza A(H5N1) viruses cross-reactive antibody response pandemic risk assessment neuraminidase inhibition antibody respiratory infections influenza A(H1N1)pdm09 |
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Snippet | We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from... |
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SubjectTerms | Adult Animals Antibodies Antibodies, Viral Avian flu Birds Blood & organ donations clade 2.3.4.4.b Dispatch Health care Humans Infections influenza Influenza A Virus, H1N1 Subtype Influenza A Virus, H5N1 Subtype influenza A(H1N1)pdm09 influenza A(H5N1) Influenza in Birds Influenza Vaccines Influenza, Human Neuraminidase Pandemics Proteins respiratory infections Risk assessment Surveillance Vaccines Viruses Zoonoses |
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Title | Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09 |
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