Stabilisers for water-in-fluorinated-oil dispersions: Key properties for microfluidic applications

Droplet-based microfluidics appears as a key emerging technology for the miniaturization and automation of biochemical assays. In terms of technology, it stands on two basic pillars: microfluidic devices on the one hand and emulsions on the other hand. Huge progress has been made on large scale inte...

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Published inCurrent opinion in colloid & interface science Vol. 20; no. 3; pp. 183 - 191
Main Authors Gruner, Philipp, Riechers, Birte, Chacòn Orellana, Laura Andreina, Brosseau, Quentin, Maes, Florine, Beneyton, Thomas, Pekin, Deniz, Baret, Jean-Christophe
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.06.2015
Elsevier
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Summary:Droplet-based microfluidics appears as a key emerging technology for the miniaturization and automation of biochemical assays. In terms of technology, it stands on two basic pillars: microfluidic devices on the one hand and emulsions on the other hand. Huge progress has been made on large scale integration of devices and batch production of devices. The limiting factor for a full application of the technology is actually not device development, but rather the robust control of emulsion formulations to be used in these devices. We here review the basic problems related to emulsions relevant for microfluidic applications and open up on new promising applications for these systems. [Display omitted] •Water in perfluorinated oil emulsions have a huge potential in microfluidics.•Retention of solutes in water droplets is controlled by surfactant molecules.•Stabilisers (eg. nanoparticles) are attractive options for droplet stabilisation.
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ISSN:1359-0294
1879-0399
DOI:10.1016/j.cocis.2015.07.005