Progress on the research and development of plague vaccines with a call to action

There is a compelling demand for approved plague vaccines due to the endemicity of Yersinia pestis and its potential for pandemic spread. Whilst substantial progress has been made, we recommend that the global funding and health security systems should work urgently to translate some of the efficaci...

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Bibliographic Details
Published innpj vaccines Vol. 9; no. 1; pp. 162 - 13
Main Authors Williamson, E. Diane, Kilgore, Paul B., Hendrix, Emily K., Neil, Blake H., Sha, Jian, Chopra, Ashok K.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 07.09.2024
Nature Publishing Group
Nature Portfolio
Subjects
631/250/255/1318
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Antibiotics
Antigens
Bacteria
Biomedical and Life Sciences
Biomedicine
Disease
Epidemics
Epidemiology
Infections
Infectious Diseases
Medical Microbiology
Pandemics
Pathogens
Plasmids
Proteins
Public Health
R&D
Research & development
Review Article
Toxins
Vaccine
Vaccines
Virology
Virulence
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Summary:There is a compelling demand for approved plague vaccines due to the endemicity of Yersinia pestis and its potential for pandemic spread. Whilst substantial progress has been made, we recommend that the global funding and health security systems should work urgently to translate some of the efficacious vaccines reviewed herein to expedite clinical development and to prevent future disastrous plague outbreaks, particularly caused by antimicrobial resistant Y. pestis strains. Content includes material subject to Crown Copyright © 2024.This is an open access article under the Open Government License ( http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/ ).
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ISSN:2059-0105
2059-0105
DOI:10.1038/s41541-024-00958-1