Changes in blood profile in sheep receiving raw garlic, garlic oil or monensin

• Published in: Journal of animal physiology and animal nutrition Vol. 99; no. 1; pp. 114 - 122
• Main Authors: Anassori, E, Dalir‐Naghadeh, B, Pirmohammadi, R, Hadian, M
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Science 01.02.2015; Blackwell Publishing Ltd; Wiley Subscription Services, Inc
• Subjects: 3-hydroxybutyric acid; 3-Hydroxybutyric Acid - blood; additives; albumins; alfalfa hay; Allyl Compounds - pharmacology; Animal Feed - analysis; Animal Nutritional Physiological Phenomena; Animals; blood; Blood Glucose; blood serum; cholesterol; corn silage; crude protein; diet; Diet - veterinary; energy balance; Fatty Acids, Nonesterified - blood; free fatty acids; garlic; Garlic - chemistry; garlic oil; glucose; insulin; Male; metabolizable energy; monensin; Monensin - pharmacology; oils; rams; sheep; Sheep - blood; Sulfides - pharmacology; triacylglycerols; urea nitrogen; monensin; garlic; garlic oil; blood; sheep
• ISSN: 0931-2439; 1439-0396
• DOI: 10.1111/jpn.12189

This study aimed to evaluate the effects of supplementing a basal diet (CTR) with raw garlic (GAR) or garlic oil (GAO) on blood profile in sheep. Monensin (MON, 33 mg/kg DM) was used as positive control. Four ruminally fistulated rams were used in three experiments each arranged in a 4 × 4 Latin square design with 28‐day periods. Experiments 1 and 2 differed in the dose of GAR (75 vs. 100 g/kg DM) and GAO (500 vs. 750 mg/kg DM), while experiment 3 was designed to compare the two doses of each additive (GAR and GAO). The animals were fed a basal diet as TMR consisting of 77.83% forage (alfalfa hay and corn silage) and 22.17% concentrate, providing 10.50 MJ/kg DM (metabolizable energy) and 16.5% crude protein to cover maintenance energy and protein requirements. Supplementation of monensin decreased (P < 0.05) β‐hydroxybutyrate (BHB) and non‐esterified fatty acid (NEFA) concentrations in the blood compared with other treatments. There was no significant effect of additives on serum concentration of glucose, total triglycerides, cholesterol, total protein, albumin and blood urea nitrogen (BUN). Although the serum insulin concentration was elevated in sheep receiving MON and GAO (P < 0.01), no change was observed in blood glucose concentration. No significant effect of GAO and GAR was observed in key energy and protein‐related blood metabolites. However, administration of monensin had a positive influence on energy indices. In conclusion, whereas parameters characterizing the energy balance did not show a significant effect of GAR supplementation, a higher insulin concentration in GAO‐treated animals was observed.