Role of risk factors proximate to time of trauma in the course of PTSD and MDD symptoms following traumatic injury

• Published in: Journal of traumatic stress Vol. 24; no. 4; pp. 390 - 398
• Main Authors: Norman, Sonya B., Trim, Ryan S., Goldsmith, Abigail A., Dimsdale, Joel E., Hoyt, David B., Norman, Gregory J., Stein, Murray B.
• Format: Journal Article
• Language: English
• Published: Germantown Wiley Subscription Services, Inc., A Wiley Company 01.08.2011; Wiley; Wiley Subscription Services, Inc
• Subjects: Adolescent; Adult; Adult and adolescent clinical studies; Aged; Anxiety disorders. Neuroses; Biological and medical sciences; California - epidemiology; Depression; Depressive Disorder, Major - epidemiology; Depressive Disorder, Major - etiology; Depressive Disorder, Major - physiopathology; Female; Humans; Male; Medical sciences; Middle Aged; Mood disorders; Pain - psychology; Post traumatic stress disorder; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Risk Factors; Stress Disorders, Post-Traumatic - epidemiology; Stress Disorders, Post-Traumatic - etiology; Stress Disorders, Post-Traumatic - physiopathology; Surveys and Questionnaires; Wounds and Injuries - psychology; Young Adult; United States; North America; America; California; Mood disorder; Social environment; Human; Anxiety disorder; Mental health; Depression; Posttraumatic stress disorder; Trauma; Stress; Symptomatology; Follow up study; Risk factor; Evolution; Lesion; Public health
• ISSN: 0894-9867; 1573-6598
• DOI: 10.1002/jts.20669

Questions exist regarding whether posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are unique sequelae of trauma or a manifestation of a single form of psychopathology. Using latent growth modeling, we examined the role of risk factors occurring within 48 hours of the time of trauma on the course of PTSD and MDD symptoms over an 8‐month period in 163 participants recruited from a level 1 surgical trauma center. Both PTSD and MDD symptoms showed peak prevalence by 1 month and significantly decreased over 7 months. Greater postinjury pain and PTSD symptoms (measured within 48 hours of trauma) predicted higher rates of both PTSD and MDD symptoms at 1 month. Other predictors were unique to each disorder. Results suggest that PTSD and MDD are related consequences of trauma. Traditional and Simplified Chinese s by AsianSTSS