Monitoring pregnancy in twinning pygmy loris (Nycticebus pygmaeus) using fecal estrogen metabolites

• Published in: American journal of primatology Vol. 46; no. 2; pp. 173 - 183
• Main Authors: Jurke, Mike H., Czekala, Nancy M., Jurke, Susanna, Hagey, Lee R., Lance, Valentine A., Conley, Alan J., Fitch-Snyder, Helena
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 1998; Wiley-Liss
• Subjects: Animal, plant and microbial ecology; Animals; aromatase; Biological and medical sciences; Estrone - analogs & derivatives; Estrone - analysis; fecal estrogen; Feces - chemistry; Female; Fundamental and applied biological sciences. Psychology; General aspects. Techniques; gestation; Gestational Age; HPLC; Lorisidae - physiology; Methods and techniques (sampling, tagging, trapping, modelling...); Nycticebus pygmaeus; placenta; Pregnancy; Pregnancy Tests - veterinary; Pregnancy, Animal; Primates; Prosimians; pygmy loris; Southeast Asia; Twins; Methodology; Enzyme; Estrogen; Lemuroidea; Estrogen synthase; Pregnancy; Reproduction; Vertebrata; Mammalia; Placenta; Enzymatic activity; Investigation method; Primates; Estrone; Feces; Sex steroid hormone
• ISSN: 0275-2565; 1098-2345
• DOI: 10.1002/(SICI)1098-2345(1998)46:2<173::AID-AJP7>3.0.CO;2-T

Estrone and estrone conjugates were measured in the feces of three female pygmy lorises (Nycticebus pygmaeus) throughout estrus, pregnancy, and the postpartum period. Two females gave birth to twins, while the third had a single stillborn. A comparison between the hormonal profiles of these three pregnancies with each other and with previously reported pregnancies resulting in singletons or twins [Jurke et al., American Journal of Primatology 41:103–115, 1997] revealed a characteristic pattern of hormonal excretion. This report adds data to and confirms previous claims that monitoring estrone in this species provides a tool to assess gestation length (via determination of estrus period) and to predict the date of parturition and the number of offspring. However, there was an exceptional case of a pregnancy which had the hormonal appearance of a twin pregnancy but resulted in a single stillborn infant. This case prompted us to search for new insights into the characteristics and the origin of the estrogens that are excreted into the feces. Aromatase activity was evaluated in five partial placentae. Am. J. Primatol. 46:173–183, 1998. © 1998 Wiley‐Liss, Inc.