Bovine Circadian Locomotor Output Cycles Kaput (CLOCK) and Clusterin (CLU) mRNA Quantitation in Ejaculated Crossbred Bull Spermatozoa
Mammalian circadian locomotor output cycles kaput (CLOCK) gene encodes a transcription factor that affects both the persistence and the period of circadian rhythms. Earlier reports suggested that CLOCK gene might be associated with male infertility in human. Present investigation, for the first time...
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Published in | Reproduction in domestic animals Vol. 50; no. 3; pp. 505 - 509 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Germany
P. Parey Scientific Publishers
01.06.2015
Blackwell Publishing Ltd |
Subjects | |
Online Access | Get full text |
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Summary: | Mammalian circadian locomotor output cycles kaput (CLOCK) gene encodes a transcription factor that affects both the persistence and the period of circadian rhythms. Earlier reports suggested that CLOCK gene might be associated with male infertility in human. Present investigation, for the first time, reports that CLOCK gene expresses differentially between good and poor quality crossbred bull semen. The relative expression of CLOCK was significantly (p < 0.05) higher among good quality bull semen than motility‐impaired ones. Clusterins (CLU) are series of genes associated with a variety of physiological activities including spermatogenesis, apoptosis and degenerative disease conditions. In the present context, we also investigated that the expression of CLU gene was significantly (p < 0.05) higher among motility‐impaired crossbred bull semen compared to the good quality one. |
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Bibliography: | http://dx.doi.org/10.1111/rda.12522 istex:7CBD0F4C8577D9E6C60BE515A1B32B1A95E81ED6 ArticleID:RDA12522 ark:/67375/WNG-MJS3BNTQ-G Bank-funded National Agricultural Innovation Project, ICAR, New Delhi ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0936-6768 1439-0531 |
DOI: | 10.1111/rda.12522 |