Early colonization of dental implants by putative periodontal pathogens in partially edentulous patients

• Published in: Clinical oral implants research Vol. 11; no. 6; pp. 511 - 520
• Main Authors: Van Winkelhoff, Arie J., Goené, Ronnie J., Benschop, Claudia, Folmer, Tiddo
• Format: Journal Article
• Language: English
• Published: Copenhagen Munksgaard International Publishers 01.12.2000
• Subjects: Aged; Aggregatibacter actinomycetemcomitans - growth & development; Alveolar Bone Loss - microbiology; bacterial colonization; Bacteroides - growth & development; Dental Fistula - microbiology; dental implants; Dental Implants - microbiology; Dental Prosthesis, Implant-Supported - microbiology; Dentistry; Denture, Partial - microbiology; Equipment Contamination; Female; Follow-Up Studies; Fusobacterium nucleatum - growth & development; Humans; Jaw, Edentulous, Partially - rehabilitation; Jaw, Edentulous, Partially - surgery; Male; Middle Aged; Peptostreptococcus - growth & development; Periodontal Index; Periodontal Pocket - microbiology; Periodontitis - microbiology; Porphyromonas gingivalis; Porphyromonas gingivalis - growth & development; Prevotella intermedia - growth & development; Saliva - microbiology; Titanium
• ISSN: 0905-7161; 1600-0501
• DOI: 10.1034/j.1600-0501.2000.011006511.x

There is limited scientific information available on the early colonization of the peri‐implant pockets in partially edentulous individuals. Knowledge about this process is one step in better understanding the etiology and pathogenesis of peri‐implantitis. In this study, the early colonization of the peri‐implant pockets by putative periodontal pathogens was studied in 20 partially edentulous individuals using anaerobic culture techniques. At baseline, the presence and levels of putative periodontal pathogens in the microflora of periodontal pockets and saliva were established. Immediately after loading of the titanium implants and after 6 and 12 months the presence and levels of selected putative periodontal pathogens were determined in periodontal and peri‐implant pockets. A second aim was to detect bacterial contamination of the implant site and the inside of the implant. At baseline, the most frequently isolated species from the periodontal pockets were Fusobacterium nucleatum, Prevotella intermedia and Peptostreptococcus micros. Bacteroides forsythus, Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis were isolated from 9, 2 and 3 patients respectively. Six months after placing of the bridges, the majority of the implant sites had detectable levels of most periodontal bacterial species with the exception of A. actinomycetemcomitans which could not be isolated from any of the peri‐implant samples during the experimental period, although 2 patients had this organism at baseline. In 2 patients with detectable subgingival P. gingivalis at baseline this species was found after 12 months in the peri‐implant sites. One of these patients lost 2 implants which was associated with a high proportion of P. gingivalis in the peri‐implant pockets. A second patient developed 2 fistulas around 2 implants at 8 months and this event was also associated with the presence of P. gingivalis. It is concluded that proper periodontal infection control before instalment of dental implants in partially edentulous patients may prevent early bacterial complications.