Flow cytometric analysis of a localized malignant mesothelioma

Malignant mesothelioma usually presents as a diffuse neoplasm. We report a localized malignant mesothelioma in the parietal pleura of a patient who was not exposed to asbestos. A complete clinical, pathologic, and immunohistochemical description is provided. Flow cytometric analysis showed an aneupl...

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Bibliographic Details
Published inThe Annals of thoracic surgery Vol. 73; no. 4; pp. 1292 - 1294
Main Authors GOMEZ-ROMAN, José Javier, MONSLERA, Roberto, SECO OLMEDO, Isabel, FERNANDO VAL-BERNAL, José
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Science 01.04.2002
Subjects
Aneuploidy
Biological and medical sciences
Diagnosis, Differential
DNA, Neoplasm - analysis
Flow Cytometry
Humans
Immunohistochemistry
Male
Medical sciences
Mesothelioma - chemistry
Mesothelioma - genetics
Mesothelioma - pathology
Middle Aged
Pleural Neoplasms - chemistry
Pleural Neoplasms - genetics
Pleural Neoplasms - pathology
Pneumology
Tumors of the respiratory system and mediastinum
Human
Pathology
Flow cytometry
Malignant mesothelioma
Respiratory disease
Cytology
Pleural disease
Exploration
Malignant tumor
Diagnosis
Pleura
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Summary:Malignant mesothelioma usually presents as a diffuse neoplasm. We report a localized malignant mesothelioma in the parietal pleura of a patient who was not exposed to asbestos. A complete clinical, pathologic, and immunohistochemical description is provided. Flow cytometric analysis showed an aneuploid DNA content in neoplastic cells. The patient is alive and well 8 months after complete surgical resection. Localized malignant mesothelioma must be included in the differential diagnosis in chest wall-based neoplasms.
Bibliography:ObjectType-Case Study-2
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ISSN:0003-4975
1552-6259
DOI:10.1016/s0003-4975(01)03261-1