Gaining access to the periphery of the lung: Bronchoscopic and transthoracic approaches

• Published in: Annals of thoracic medicine Vol. 12; no. 3; pp. 162 - 170
• Main Authors: Touman, Abdelfattah Ahmed, Vitsas, Vlasios V, Koulouris, Nickolaos G, Stratakos, Grigoris K
• Format: Journal Article
• Language: English
• Published: India Medknow Publications & Media Pvt. Ltd 01.07.2017; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Biopsy; Bronchoscopic modalities; Drug dosages; image-guided transthoracic needle aspiration; interventional pulmonology; Lung cancer; Medical imaging; Medical prognosis; Mortality; navigation bronchoscopy; peripheral lung nodule; Review; Ultrasonic imaging; lung cancer; navigation bronchoscopy; peripheral lung nodule; Bronchoscopic modalities; interventional pulmonology; image-guided transthoracic needle aspiration
• ISSN: 1817-1737; 1998-3557
• DOI: 10.4103/atm.ATM_416_16

Globally, lung cancer remains the leading cause of cancer-related death. Annual low-dose computed tomography has been recommended as a screening test for early detection of lung cancers. Implementing this screening strategy is expected to challenge pulmonologist to confirm the nature of the increasing number of detected pulmonary nodules. Clinicians are obliged to use the less invasive and most efficient and safe means to set diagnoses. Hence, the field of diagnostic modalities, especially the advanced diagnostic bronchoscopy is witnessing rapid evolution to fulfill these unmet needs. This review highlights the available diagnostic modalities, describes their advantages and discusses the limitations of each technique. It also suggests an integrated diagnostic algorithm based on the best available evidence. A search of the PubMed database was conducted using relevant terms described at methodology; only articles in English were reviewed by November 2016.