Direct growth of graphene on quartz substrates for label-free detection of adenosine triphosphate

• Published in: Nanotechnology Vol. 25; no. 16; pp. 165702 - 10
• Main Authors: Xu, Shicai, Man, Baoyuan, Jiang, Shouzhen, Yue, Weiwei, Yang, Cheng, Liu, Mei, Chen, Chuansong, Zhang, Chao
• Format: Journal Article
• Language: English
• Published: Bristol IOP Publishing 25.04.2014; Institute of Physics
• Subjects: Adenosine triphosphate; Adenosine Triphosphate - chemistry; ATP; Biosensing Techniques - methods; Biosensors; Chemical vapor deposition; Chemical vapor deposition (including plasma-enhanced cvd, mocvd, etc.); Condensed matter: electronic structure, electrical, magnetic, and optical properties; Cross-disciplinary physics: materials science; rheology; Devices; Exact sciences and technology; Fullerenes and related materials; Fullerenes and related materials; diamonds, graphite; Graphene; Graphite - chemistry; Infrared and raman spectra and scattering; Materials science; Methods of deposition of films and coatings; film growth and epitaxy; Optical properties and condensed-matter spectroscopy and other interactions of matter with particles and radiation; Partial pressure; Particle Size; Physics; Quartz; Quartz - chemistry; Specific materials; Surface Properties; Temperature; two-temperature zone; Visible and ultraviolet spectra; Ultrathin films; Grain size; Raman spectra; Catalysts; Hall effect; Raman spectroscopy; Precursor; Time response; Thin films; CVD; Transmission electron microscopy; Partial pressure; Graphene; Monolayers; Growth mechanism; Absorption spectra; Biosensors; Carrier mobility
• ISSN: 0957-4484; 1361-6528; 1361-6528
• DOI: 10.1088/0957-4484/25/16/165702

We demonstrate that continuous, uniform graphene films can be directly synthesized on quartz substrates using a two-temperature-zone chemical vapor deposition system and that their layers can be controlled by adjusting the precursor partial pressure. Raman spectroscopy and transmission electron microscopy confirm the formation of monolayer graphene with a grain size of 100 nm. Hall measurements show a room-temperature carrier mobility above 1500 cm2 V−1 s−1. The optical transmittance and conductance of the graphene films are comparable to those of transferred metal-catalyzed graphene. The method avoids the complicated and skilled post-growth transfer process and allows the graphene to be directly incorporated into a fully functional biosensor for label-free detection of adenosine triphosphate (ATP). This device shows a fast response time of a few milliseconds and achieves a high sensitivity to ATP molecules over a very wide range from 0.002 to 5 mM.