Efficacy of low doses of praziquantel in taeniasis

• Published in: Acta Tropica Vol. 48; no. 2; pp. 83 - 88
• Main Author: Pawowski, Zbigniew S
• Format: Book Review Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.12.1990; Elsevier
• Subjects: Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiparasitic agents; Biological and medical sciences; Humans; Low dose; Medical sciences; Pharmacology. Drug treatments; Praziquantel; Praziquantel - administration & dosage; Praziquantel - therapeutic use; Taeniasis - drug therapy; Taeniasis in man; Praziquantel; Low dose; Taeniasis in man; Cestod disease; Infection; Human; Chemotherapy; Anthelmintic; Treatment; Digestive diseases; Teniasis; Helminthiasis

Early experimental studies suggested that doses of 1 to 5 mg of praziquantel (PZQ) per kg are effective against several intestinal cestodiases. The usually recommended single dose of PZQ in human taeniasis is 5 or 10 mg/kg. A study in T. saginata taeniasis showed a full efficacy at a dose of 2.5 mg/...