Effect of aortic valve replacement on c-reactive protein in nonrheumatic aortic stenosis

• Published in: The American journal of cardiology Vol. 92; no. 9; pp. 1129 - 1132
• Main Authors: Gerber, Ivor L., Stewart, Ralph A.H., Hammett, Christopher J.K, Legget, Malcolm E., Oxenham, Helen, West, Teena M., French, John K., White, Harvey D.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2003; Elsevier; Elsevier Limited
• Subjects: Adult; Aged; Aortic Valve Insufficiency - blood; Aortic Valve Insufficiency - diagnosis; Aortic Valve Insufficiency - surgery; Aortic Valve Stenosis - blood; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - surgery; Biological and medical sciences; C-Reactive Protein - metabolism; Cardiology. Vascular system; Cardiovascular disease; Effects; Endocardial and cardiac valvular diseases; Female; Heart; Heart Valve Prosthesis Implantation; Humans; Male; Medical sciences; Middle Aged; Proteins; Rheumatic Heart Disease - blood; Rheumatic Heart Disease - diagnosis; Rheumatic Heart Disease - surgery; Severity of Illness Index; Aortic stenosis; Cardiac valvular disease; Cardiovascular disease; Replacement; Circulatory system; Cardiology; C reactive protein; Phlebology; Aortic valve
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2003.07.012

Plasma levels of C-reactive protein were higher in 20 patients with bicuspid or trileaflet degenerative aortic stenosis than in 31 normal controls and in 19 patients with pure aortic regurgitation. C-reactive protein decreased from before to 6 months after aortic valve replacement for aortic stenosis. These observations suggest that aortic stenosis is an inflammatory disease.