Molecular Characterization of Trypanosoma cruzi Reactivation and Follow-up in a Case Series of People With HIV

Abstract We characterize Trypanosoma cruzi infections from blood and cerebrospinal fluid samples in a case series of people with human immunodeficiency virus and Chagas disease. We identify different infecting T. cruzi populations, highlighting the usefulness of real-time polymerase chain reaction f...

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Published inOpen forum infectious diseases Vol. 10; no. 8; p. ofad357
Main Authors Fernandez, Marisa Liliana, Albizu, Constanza Lopez, Nicita, Diego, Besuschio, Susana, Giomi, Cinthia, Biondi, María Laura, Leguizamón, María Susana, Garcia, Julian, Corti, Marcelo, Schijman, Alejandro, Burgos, Juan Miguel
Format Journal Article
LanguageEnglish
Published US Oxford University Press 01.08.2023
Subjects
Brief Report
Chagas' disease
Ethylenediaminetetraacetic acid
HIV (Viruses)
HIV patients
Argentina
Chagas disease reactivation
qPCR
people with HIV
Trypanosoma cruzi
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Summary:Abstract We characterize Trypanosoma cruzi infections from blood and cerebrospinal fluid samples in a case series of people with human immunodeficiency virus and Chagas disease. We identify different infecting T. cruzi populations, highlighting the usefulness of real-time polymerase chain reaction for Chagas disease reactivation diagnosis and evaluation of treatment response.
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Presented in part: 52nd Congress of the Brazil Society of Tropical Medicine, Maceio, Brazil, August 2016.
Potential conflicts of interest. All authors report no potential conflicts of interest.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofad357