Successful Treatment with Integrated Chinese and Western Medicine for Severe Overdose of Amlodipine： A Case Report

Introduction Amlodipine is a dihydropyridine calcium channel blocker （CCB） that inhibits calcium influx into cardiac, vascular smooth muscle cells, and pancreatic beta cells, leading to dilation of arteries and arterioles and reduction in insulin secretion. Oral administration of amlodipine is absor...

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Published inChinese journal of integrative medicine Vol. 21; no. 9; pp. 703 - 706
Main Author 赖芳 张燕 谢东平 李芳 韩云
Format Journal Article
LanguageEnglish
Published Beijing Chinese Association of Traditional and Western Medicine 01.09.2015
Subjects
Adult
Aged
Amlodipine - adverse effects
Case Report
Drug Overdose - diagnostic imaging
Drug Overdose - drug therapy
Drugs, Chinese Herbal - therapeutic use
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Radiography, Thoracic
Treatment Outcome
中西医结合治疗
景区
氨氯地平
Amlodipine
Calcium Gluconate
Levosimendan
Amlodipine Besylate
Calcium Infusion
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Summary:Introduction Amlodipine is a dihydropyridine calcium channel blocker （CCB） that inhibits calcium influx into cardiac, vascular smooth muscle cells, and pancreatic beta cells, leading to dilation of arteries and arterioles and reduction in insulin secretion. Oral administration of amlodipine is absorbed slowly but almost completely, with a hiah oral bioavailabilitv up to 60%-80%.
Bibliography:Introduction Amlodipine is a dihydropyridine calcium channel blocker （CCB） that inhibits calcium influx into cardiac, vascular smooth muscle cells, and pancreatic beta cells, leading to dilation of arteries and arterioles and reduction in insulin secretion. Oral administration of amlodipine is absorbed slowly but almost completely, with a hiah oral bioavailabilitv up to 60%-80%.
11-4928/R
LAI Fang , ZHANG Yan, XIE Dong-ping , LI Fang , HAN Yun （Intensive Care Unit, Fangcun Branch Hospital, Guangdong ProvincialHospital of Chinese Medicine, Guangzhou （510145）, China）
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:1672-0415
1993-0402
1993-0402
DOI:10.1007/s11655-015-2130-5