The Relationship between Mushroom Intake and Cognitive Performance: An Epidemiological Study in the European Investigation of Cancer-Norfolk Cohort (EPIC-Norfolk)

• Published in: Nutrients Vol. 16; no. 3; p. 353
• Main Authors: Cha, Sara, Bell, Lynne, Williams, Claire M
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.01.2024
• Subjects: Aging; Cancer; Chronic diseases; Citrus; Citrus fruits; Cognitive ability; cognitive performance; Diet; epidemiological; Epidemiology; Executive function; Food; Food habits; Fruits; global memory; Investigations; Marketing research; Memory; Mental health; mushroom intake; Mushrooms; older adults; Oncology, Experimental; Public health; Questionnaires; Surveys; Vegetables; United Kingdom; Japan; mushroom intake; older adults; global memory; epidemiological; cognitive performance
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu16030353

The previous literature suggests that regular consumption of edible mushrooms may confer neuroprotective cognitive health benefits. To further investigate the possible association between mushrooms and brain function during ageing, data from a population-based study of diet and chronic disease (EPIC-Norfolk cohort) were analysed. Changes in mushroom intake were measured using a food frequency questionnaire at three health check (HC) points over an 18-year period, with participants categorised based on their consumption frequency. Cognitive performance was assessed at the final health check (3HC) via a battery of validated tests assessing a range of different cognitive domains. The findings revealed a significant reduction in mushroom intake over time, with 4.12% of the cohort giving up mushrooms after previously consuming them. At 3HC, mushroom consumers displayed better cognitive performance than non-consumers across multiple cognitive domains. This relationship was observed to be dose-dependent, with those consuming 1 or more portions per week showing the highest cognitive scores. These findings suggest that regular mushroom consumption may be beneficial for cognitive function during aging. Further randomised controlled trials will be needed to confirm any potential benefits of mushrooms on long-term cognitive health, alongside public health initiatives to promote mushroom consumption in this older-adult demographic.