Assessment of Gnaphalium viscosum (Kunth) Valorization Prospects: Sustainable Recovery of Antioxidants by Different Techniques

• Published in: Antioxidants Vol. 11; no. 12; p. 2495
• Main Authors: Boyadzhieva, Stanislava, Coelho, Jose A P, Errico, Massimiliano, Reynel-Avilla, H Elizabeth, Yankov, Dragomir S, Bonilla-Petriciolet, Adrian, Stateva, Roumiana P
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.12.2022; MDPI
• Subjects: Antioxidants; Biomass; biomass valorization; Carotenoids; Chlorogenic acid; Chromatography; Cytotoxicity; Ethanol; Fatty acids; Flavonoids; Flowers; Flowers & plants; Gnaphalium; Herbal medicine; Kaempferol; Metabolites; Mexican Gordolobo; Phenolic compounds; phytochemicals; Solvents; supercritical CO2 extraction; Mexico; biomass valorization; phytochemicals; supercritical CO2 extraction; fatty acids; antioxidants; Mexican Gordolobo
• ISSN: 2076-3921; 2076-3921
• DOI: 10.3390/antiox11122495

This work investigates the prospects for exploitation of (Kunth) abundant but with limited applications till present biomass. The feasibility of traditional techniques (two-phase solvent, and the benchmark Soxhlet extraction) and supercritical extraction without/with a cosolvent at = 40-60 °C and = 30-50 MPa was examined to explore the possibility of recovering phytochemicals from leaves, flowers and stems. The efficiency of the techniques was assessed and compared based on yield, influence of solvents used, total phenolic content and antioxidant activity of the extracts. Phenolics of different complexities were identified and quantified by applying LC (LC-MS/MS, and LC-HRAM), while the fatty acid profile was determined by GC-FID. The results of this extensive study demonstrated the huge valorization potential and prospects of , since highly potent antioxidants such as kaempferol, kaempferol-3-O-β-d-glucoside (astragalin), and chlorogenic acid were ascertained in considerable amounts. Furthermore, for the first time, the presence of leontopodic acid, a greatly substituted derivative of glucaric acid, was detected in the species.